AT-Port

The challenge of aseptic liquid connection

Aseptic liquid transfer is a day-to-day operation during manufacturing of pharmaceutical liquid/injectable products to ensure a safe & sterile transfer of the final solution.

Broad use of barrier isolation technologies (isolators, RABS) for securing the critical aseptic processes, as formulation or filling, is associated with challenges of aseptic liquid transfer across the stainless-steel shell, requiring solid validation data, high flexibility and minimized dead volume.

AT-Port System

The AT-Port System is an alpha-beta aseptic liquid connection system, enabling safe liquid transfer between different containment classification areas, across a wall, while maintaining sterility.
It consists of the :

  • Connector Port
  • Disposable Connector Devices, AT-Connector and AT-Connect

Watch the video

AT-Port™_1

Transfer larger volumes: AT-Connector

  • For large volumes liquid transfer between two different classification environments
  • Same connector can be used up to 5 opening-closing operations
  • Hose barb connections
  • Supplied sterilized or non-sterilized for RTU assembly
  • Distributed worldwide by Sartorius Stedim under brand name Gammasart Aseptic Transfer Device (ATD™)

When every drop matters: AT-Connect

  • Aseptic liquid connector device used with AT-Port System
  • For optimal high-value bulk product introduction to the aseptic filling line, installed on isolator or RABS.
  • Efficient low volume transfer
  • Product contact with silicone and thermoplastic elastomer (C-Flex®) tubing only: tube passes through the disposable connector device
  • Enables placement of the dosing system outside of the containment

Advantages

  • Ergonomic design
  • 100% leak-test of the system
  • Small footprint
  • Connection is made in seconds
  • Ensuring grade A continuity
  • Error-proofing with security features
Webinars

AT-Closed Vial® and Container Closure Integrity during Cryogenic Storage

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