Company

Main milestones

2002

Creation of Aseptic Technologies as a spin-out of GSK Biologicals S.A.

2003

First introduction of the concept of the Closed Vial to the American FDA and to the EMA (Europe).

2004

First prototype of a filling machine based on the Closed Vial concept. 

2005

First successful medial fill using the prototype. Presentation of validation data to the FDA.

2006

Inauguration of our aseptic filling facility equipped with a Closed Vial Filling Line.

2007

Our Crystal^® filling facility is approved as GMP manufacturing site by EMA. DMF filed at CBER and CDER.

2008

Launch of development programs for laboratory scale equipment.

2009

Our GMP approved filling suite wins the ISPE Facility Of the Year Award - Equipment Innovation.
In December, the first Crystal^® M1 Filling Station is delivered to Lonza, Walkersville (MD, USA).

2010

Delivery of the first robotic to the Netherlands Vaccine Institute (NVI).
Decision to extend the vial range up to 50ml.

2011

SKAN AG becomes the main shareholder of Aseptic Technologies.
The GSK Synflorix^® pediatric vaccine is approved in the AT-Closed Vial^® in Europe.

2012

First application in Hospital at Hopitaux Universitaires de Genève (HUG), CH.
Training course to American FDA inspectors about the Closed Vial Technology.

2013

First prototype of the Crystal^® PX Production Line.
The second generation of the Crystal^® M1 Filling Station is launched.        

2014

Delivery of the 50^th Crystal^® M1 Filling Station. 
80% of all GSK Vaccines are getting through our aseptic connector.     

2015

First order for the new Crystal^® L1 Robot Line. First equipment installed in Japan.     

2016

Delivery of the 100^th Crystal^®, at the University of Alberta in Canada.
Crystal^® L1 Robot Line ordered for US, Spain, Japan and South Korea.

Our activities

Aseptic Technologies develops, patents, manufactures and markets equipment that guarantee optimal aseptic assurance and complies with last regulatory requirements, while simplifying the validation and operation processes in the safest way.

At Aseptic Technologies we are proud of the AT-Closed Vial^® Technology: filling pre-sterilized vials to significantly reduce the risk of batch contamination while simplifying the fill and finish of your drug product. 

Besides it, we manufacture other aseptic filling-related products, such as filling kits (AT-Filling Kit™) and aseptic connecting systems (AT-Connector™ System) used to transfer sterile liquids across separation walls.

Since 2015 we collaborate with SKAN in development new platforms combining our respective technologies with the aim of offering integrated solutions, fulfilling the future expectations of the Industry.

Aseptic Technologies is ISO 9001 certified. 

Our Partners 

 1968 founded SKAN AG belongs to those pioneer companies in the special area of cleanroom equipment and construction of Isolators for the pharmaceutical chemical industry. Innovative products, client specific solutions as well as results capable products and service organization made SKAN AG a market leader and an important partner of industry and research laboratories. 

 a company headquarted in Indiana, USA, operating a facility in France (formerly owned by Rexam Healthcare Containers and Closures) specialized in Injection Blow Molding. 

a company 4 plants in Europe and the USA (formerly Rexam Healthcare Devices) specialized in injection molding. 

          a Belgian company specialized in plastic molding.

a Belgian company dedicated to new laser applications. Lasea develops, creates and produces reliable, performing, innovative solutions for industrial purposes. 

a Belgian company specialized in secondary packaging activities for the pharmaceutical industry.

a Belgian company specialized in high-end stainless steel machining.

Aseptic Technologies also share long term collaboration with some other companies such as Ateliers De Ceuster (ADC), Ateliers Baugnée S.A, Malcourant Mécanique S.A,...

Core technology for AT-Closed Vial^® Technology licensed from Medical Instill Technology Inc.